91精品福利免费在线观看,亚洲精品一区二区三区五区 ,精品一区二区不卡无av,大肉棒插插视频

資訊中心NEWS CENTER

在發(fā)展中求生存，不斷完善，以良好信譽(yù)和科學(xué)的管理促進(jìn)企業(yè)迅速發(fā)展

首頁(yè)-技術(shù)文章-Hindered Non-Standard Amino Acid的微波合成用

企業(yè)新聞技術(shù)文章

Hindered Non-Standard Amino Acid的微波合成用

更新時(shí)間：2012-06-29 點(diǎn)擊次數(shù)：2895

INTRODUCTION
The N-α-Fmoc-α-aminoisobutyric acid derivative （Aib） is a difficult derivative for coupling in SPPS due to its second methyl group on the α-carbon that interferes with the coupling reaction （Figure 1）. However, it can be found in a number of biologically relevant compounds, particularly fungal-derived peptide antibiotics such as alamethicin, so methods to successfully couple the Aib amino acid need to be developed. The use of microwave enhanced synthesis helps to drive difficult reactions like those containing the Aib amino acid to completion.

Figure 1: N-α-Fmoc-α-aminoisobutyric acid